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Neonatal hypoxic-ischemic encephalopathy HIE is the result of a global hypoxic-ischemic brain injury in a term neonate, usually after asphyxia. It is important to remember that neonatal encephalopathy may result from a variety of conditions and hypoxic-ischemic brain injury is the most important of them 1. Consequently, both terms are frequently used as synonyms. Hypoxic-ischemic encephalopathy is one of the most common causes of cerebral palsy and other severe neurological deficits in children, occurring in of every live births. The encephalopathic neonate may have low Apgar scores at delivery and metabolic acidosis documented in the cord blood. Within the first 24 hours of life, the infant may develop symptoms of apnea and seizures with abnormal electroencephalographic EEG results.
Neuroprotective body hypothermia among newborns with hypoxic ischemic encephalopathy: three-year experience in a tertiary university hospital. A retrospective observational study. Um estudo observacional retrospectivo. I MD, MSc. IV MD. Neonatal hypoxic-ischemic encephalopathy is associated with high morbidity and mortality. Studies have shown that therapeutic hypothermia decreases neurological sequelae and death.